1,833 research outputs found
Before the Morning After
This paper presents a wearable biopatch prototype for body surface potential measurement. It combines three key technologies, including mixed-signal system on chip (SoC) technology, inkjet printing technology, and anisotropic conductive adhesive (ACA) bonding technology. An integral part of the biopatch is a low-power low-noise SoC. The SoC contains a tunable analog front end, a successive approximation register analog-to-digital converter, and a reconfigurable digital controller. The electrodes, interconnections, and interposer are implemented by inkjet-printing the silver ink precisely on a flexible substrate. The reliability of printed traces is evaluated by static bending tests. ACA is used to attach the SoC to the printed structures and form the flexible hybrid system. The biopatch prototype is light and thin with a physical size of 16 cm x 16 cm. Measurement results show that low-noise concurrent electrocardiogram signals from eight chest points have been successfully recorded using the implemented biopatch.QC 20130805. Updated from accepted to published.</p
A Model of Two-Way Selection System for Human Behavior
We propose a model of two-way selection system. It appears in the processes
like choosing a mate between men and women, making contracts between job
hunters and recruiters, and trading between buyers and sellers. In this paper,
we propose a model of two-way selection system, and present its analytic
solution for the expectation of successful matching total and the regular
pattern that the matching rate trends toward an inverse proportion to either
the ratio between the two sides or the ratio of the state total to the smaller
people number. The proposed model is verified by empirical data of the
matchmaking fairs. Results indicate that the model well predicts this typical
real-world two- way selection behavior to the bounded error extent, thus it is
helpful for understanding the dynamics mechanism of the real-world two-way
selection system.Comment: 8 pages, 4 figure
Functional examination of novel kisspeptin phosphinic peptides
Kisspeptins acting on their cognate G protein-coupled receptor, kisspeptin receptor, play important roles in the suppression of cancer cell metastasis and regulation of the reproductive system, and therefore are important for therapeutic intervention. All native functional human kisspeptins (kisspeptin-54, kisspsptin-14 and kisspeptin-13) share the 10 amino acids of kisspeptin-10 at their C-terminus (45ā54). However, they are inactivated rapidly by matrix metalloproteinases (MMPs) through the cleavage of the peptide bond between glycine51 and leucine52, which limits their clinical applications. Development of MMP-resistant analogues of kisspeptins may provide better therapeutic outputs. In the present study, two kisspeptin phosphinic peptides were designed and synthesized, and their ability to induce phosphorylation of ERK1/2 through kisspeptin receptor and their inhibition on MMP-2 and MMP-9 whose activity correlates with cancer metastasis were assessed. The results showed that one analogue, phosphinic kisspeptin R isomer (PKPR), exhibited kisspeptin receptor-agonistic activity and also inhibitory activity on MMP-2, indicating that PKPR may serve as a lead for the further development of kisspeptin analogues for therapeutic purpose
Suppression of epidemic spreading in complex networks by local information based behavioral responses
This work was funded by the National Natural Science Foundation of China (Grant Nos. 61473001, 11105025, and 11331009) and the Doctoral Research Foundation of Anhui University (Grant No. 02303319). Y.C.L. was supported by AFOSR under Grant No. FA9550-10-1-0083.Peer reviewedPublisher PD
Developments of a 2D Position Sensitive Neutron Detector
Chinese Spallation Neutron Source (CSNS), one project of the 12th
five-year-plan scheme of China, is under construction in Guangdong province.
Three neutron spectrometers will be installed at the first phase of the
project, where two-dimensional position sensitive thermal neutron detectors are
required. Before the construction of the neutron detector, a prototype of
two-dimensional 200 mmx200 mm Multi-wire Proportional Chamber (MWPC) with the
flowing gas of Ar/CO2 (90/10) has been constructed and tested with the 55Fe
X-Ray using part of the electronics in 2009, which showed a good performance.
Following the test in 2009, the neutron detector has been constructed with the
complete electronics and filled with the 6atm.3He + 2.5atm.C3H8 gas mixture in
2010. The neutron detector has been primarily tested with an Am/Be source. In
this paper, some new developments of the neutron detector including the design
of the high pressure chamber, the optimization of the gas purifying system and
the gas filling process will be reported. The results and discussion are also
presented in this paper.Comment: 5 page
Ultraquantum magnetoresistance in Kramers Weyl semimetal candidate -Ag2Se
The topological semimetal -Ag2Se features a Kramers Weyl node at the
origin in momentum space and a quadruplet of spinless Weyl nodes, which are
annihilated by spin-orbit coupling. We show that single crystalline
-Ag2Se manifests giant Shubnikov-de Haas oscillations in the
longitudinal magnetoresistance which stem from a small electron pocket that can
be driven beyond the quantum limit by a field less than 9 T. This small
electron pocket is a remainder of the spin-orbit annihilatedWeyl nodes and thus
encloses a Berry-phase structure. Moreover, we observed a negative longitudinal
magnetoresistance when the magnetic field is beyond the quantum limit. Our
experimental findings are complemented by thorough theoretical band structure
analyses of this Kramers Weyl semimetal candidate, including first-principle
calculations and an effective k*p model.Comment: A new version based on arXiv:1502.0232
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